Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $84.15 | Total: $420.75 |
| 1 | 10 | $71.28 | Total: $712.80 |
| 1 | 25 | $60.39 | Total: $1,509.75 |
| 1 | 50 | $51.48 | Total: $2,574.00 |
| 1 | 100 | $44.55 | Total: $4,455.00 |
Overview
PF-06952229 is a selective inhibitor of TGF?RI. PF-06952229 can be used in studies about the treatment of solid tumors, specifically metastatic breast cancer.
Chemical Properties
| Molecular Formula | C23H24ClFN4O3 |
| Molecular Weight | 458.91 |
| CAS Numbers | 1801333-55-0 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CC(C)c1cnc(cc1Nc1ccncc1C(=O)NC(CO)CO)-c1cc(Cl)ccc1F |
Storage and Handling
0C Short Term, -20C Long Term
References
Flavia Mercer Pernasetti, et al. Combinations of tgfb inhibitors and cdk inhibitors for the treatment of breast cancer. Patent WO2020058820A1.