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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $22.10 | Total: $110.50 |
| 1 | 10 | $18.72 | Total: $187.20 |
| 1 | 25 | $15.86 | Total: $396.50 |
| 1 | 50 | $13.52 | Total: $676.00 |
| 1 | 100 | $11.70 | Total: $1,170.00 |
Overview
SMI-16a (PIM12 Kinase Inhibitor VI) , a cell-permeable thiazolidinedione compound, acts as an effective, ATP-competitive inhibitor against Pim-12 kinases (IC50: 15020 nM) while exhibiting little or no activity against a panel of 57 other kinases (?18% inhibition at 5 ?M).
Chemical Properties
| Molecular Formula | C13H13NO3S |
| Molecular Weight | 263.31 |
| CAS Numbers | 587852-28-6 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CCCOc1ccc(C=C2SC(=O)NC2=O)cc1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Xia Z., et al. Synthesis and evaluation of novel inhibitors of Pim-1 and Pim-2 protein kinases. J Med Chem. 2009 Jan 8;52[1] 74-86.