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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $107.95 | Total: $539.75 |
| 1 | 10 | $91.44 | Total: $914.40 |
| 1 | 25 | $77.47 | Total: $1,936.75 |
| 1 | 50 | $66.04 | Total: $3,302.00 |
| 1 | 100 | $57.15 | Total: $5,715.00 |
Overview
PKA Inhibitor Fragment (6-22) amide TFA (PKA Inhibitor Fragment (6-22) amide TFA) is a highly potent inhibitor of cAMP-dependent protein kinase A (PKA) with a Ki of 2.8 nM and reverses the pain-relieving effects of low levels of morphine in mice.
Chemical Properties
| Molecular Formula | C82H131F3N28O26 |
| Molecular Weight | 1982.08 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CC[C@H](C)[C@@H](C(N)=O)NC([C@H](C)NC([C@H](CC(N)=O)NC([C@H](CCCNC(N)=N)NC([C@H](CCCNC(N)=N)NC(CNC([C@H]([C@H](O)C)NC([C@H](CCCNC(N)=N)NC(CNC([C@H](CO)NC([C@H](C)NC([C@H]([C@@H](C)CC)NC([C@@H](NC([C@H](CC(O)=O)NC([C@H](C)NC([C@@H](NC([C@@H](N)[C@H](O)C)=O)CC1=CC=C(C=C1)O)=O)=O)=O)CC2=CC=CC=C2)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O |
Storage and Handling
0C Short Term, -20C Long Term
References
Dalton GD, et al. Alterations in brain Protein Kinase A activity and reversal of morphine tolerance by two fragments of native Protein Kinase A inhibitor peptide [PKI]. Neuropharmacology. 2005 Apr; 48[5] 648-57.