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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $84.15 | Total: $420.75 |
| 1 | 10 | $71.28 | Total: $712.80 |
| 1 | 25 | $60.39 | Total: $1,509.75 |
| 1 | 50 | $51.48 | Total: $2,574.00 |
| 1 | 100 | $44.55 | Total: $4,455.00 |
Overview
PKCiota-IN-2 (PKCiota-IN-49) is a selective and potent PKCiota (PKC-?) inhibitor with an IC50 of 2.8 nM. PKCiota-IN-2 also inhibits PKC-? and PKC-? with IC50s of 71 nM and 350 nM, respectively
Chemical Properties
| Molecular Formula | C24H21N5O |
| Molecular Weight | 395.46 |
| CAS Numbers | 2230055-52-2 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O(C)C1=C(C2=C3N(N=C2)C=CC(=C3)C4=C5C(=NC=C4)NC=C5)C=C6C(=C1)CCNC6 |
Storage and Handling
0C Short Term, -20C Long Term
References
Jacek Kwiatkowski, et al. Fragment-Based Drug Discovery of Potent Protein Kinase C Iota Inhibitors. J Med Chem. 2018 May 24;61[10] 4386-4396.