Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $26.35 | Total: $131.75 |
| 1 | 10 | $22.32 | Total: $223.20 |
| 1 | 25 | $18.91 | Total: $472.75 |
| 1 | 50 | $16.12 | Total: $806.00 |
| 1 | 100 | $13.95 | Total: $1,395.00 |
Overview
Cerdulatinib (PRT2070) is an novel oral dual SykJAK inhibitor.
Chemical Properties
| Molecular Formula | C20H27N7O3S |
| Molecular Weight | 445.54 |
| CAS Numbers | 1198300-79-6 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CCS(=O)(=O)N1CCN(CC1)c1ccc(Nc2ncc(C(N)=O)c(NC3CC3)n2)cc1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Guo A, et al. Dual SYKJAK inhibition overcomes ibrutinib resistance in chronic lymphocytic leukemia Cerdulatinib, but not ibrutinib, induces apoptosis of tumor cells protected by the microenvironment. Oncotarget. 2017 Feb 21;8[8] 12953-12967.