Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
- Chemokines
- Cytokine Receptors
- Biomarkers and Buffer Solutions
- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
- Apoptosis
- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
- ELISA KIT
- Natural Products
- Lab Equipments
- Humanized Mice for PDX Platform
- Rare Chemicals
- Custom Synthesis
- Antibacterial
- Antifungal
- Antioxidant
- Antiviral
- Molecular Glues
- SARS-CoV
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $54.40 | Total: $272.00 |
| 1 | 10 | $46.08 | Total: $460.80 |
| 1 | 25 | $39.04 | Total: $976.00 |
| 1 | 50 | $33.28 | Total: $1,664.00 |
| 1 | 100 | $28.80 | Total: $2,880.00 |
Overview
Mericitabine (R-7128) is a nucleoside HCV NS5B polymerase inhibitor. It acts as an RNA chain terminator and prevents the elongation of RNA transcripts during replication.
Chemical Properties
| Molecular Formula | C18H26FN3O6 |
| Molecular Weight | 399.41 |
| CAS Numbers | 940908-79-2 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CC(C)C(=O)OC[C@H]1O[C@@H](n2ccc(N)nc2=O)[C@](C)(F)[C@@H]1OC(=O)C(C)C |
Storage and Handling
0C Short Term, -20C Long Term
References
Le Pogam S, et al. Characterization of HCV quasispecies dynamics upon short term dual-therapy with the HCV NS5B nucleoside polymerase inhibitor mericitabine and the NS34 protease inhibitor danoprevir. Antimicrob Agents Chemother. 2012 Nov;56[11] 5494-5