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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $95.20 | Total: $476.00 |
| 1 | 10 | $80.64 | Total: $806.40 |
| 1 | 25 | $68.32 | Total: $1,708.00 |
| 1 | 50 | $58.24 | Total: $2,912.00 |
| 1 | 100 | $50.40 | Total: $5,040.00 |
Overview
Atabecestat (JNJ-54861911) is a potent, brain-penetrant, and orally active ?-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor that achieves robust and high CSF A? reduction, is well-tolerated, and displays sustained pharmacokinetic (PK) and pharmacodynamic (PD) characteristics. Atabecestat (JNJ-54861911) has the potential for Alzheimer's Disease treatment[1].
Chemical Properties
| Molecular Formula | C18H14FN5OS |
| Molecular Weight | 367.4 |
| CAS Numbers | 1200493-78-2 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | C[C@]1(C=CSC(N)=N1)c1cc(NC(=O)c2ccc(cn2)C#N)ccc1F |
Storage and Handling
0C Short Term, -20C Long Term
References
Timmers M, et al. Profiling the dynamics of CSF and plasma A? reduction after treatment with JNJ-54861911, a potent oral BACE inhibitor.Alzheimers Dement [N Y]. 2016 Aug 24;2[3] 202-212.