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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $22.95 | Total: $114.75 |
| 1 | 10 | $19.44 | Total: $194.40 |
| 1 | 25 | $16.47 | Total: $411.75 |
| 1 | 50 | $14.04 | Total: $702.00 |
| 1 | 100 | $12.15 | Total: $1,215.00 |
Overview
SAR-20347 is an inhibitor of TYK2 and JAK123, with IC50 values of 0.6 nM, 23 nM, 26 nM, and 41 nM, respectively.
Chemical Properties
| Molecular Formula | C21H18ClFN4O4 |
| Molecular Weight | 444.84 |
| CAS Numbers | 1450881-55-6 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | NC(=O)c1nc(oc1Nc1ccc(cc1)C(=O)N1CCOCC1)-c1c(F)cccc1Cl |
Storage and Handling
0C Short Term, -20C Long Term
References
Works MG, et al. Inhibition of TYK2 and JAK1 ameliorates imiquimod-induced psoriasis-like dermatitis by inhibiting IL-22 and the IL-23IL-17 axis. J Immunol. 2014 Oct 1;193[7] 3278-87.