Categories
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- Protein Control Ligand
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $37.40 | Total: $187.00 |
| 1 | 10 | $31.68 | Total: $316.80 |
| 1 | 25 | $26.84 | Total: $671.00 |
| 1 | 50 | $22.88 | Total: $1,144.00 |
| 1 | 100 | $19.80 | Total: $1,980.00 |
Overview
SB-435495 is an orally active, selective and potent Lp-PLA2 inhibitor (IC50 of 0.06 nM) for the study of autoimmune uveitis and atherosclerosis.
Chemical Properties
| Molecular Formula | C38H40F4N6O2S |
| Molecular Weight | 720.82 |
| CAS Numbers | 304694-39-1 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O=C1N=C(SCC2=CC=C(F)C=C2)N(C=C1CC=3C=NN(C3)C)CC(=O)N(CC4=CC=C(C=C4)C=5C=CC(=CC5)C(F)(F)F)CCN(CC)CC |
Storage and Handling
0C Short Term, -20C Long Term
References
Blackie JA, et al. The discovery of SB-435495. A potent, orally active inhibitor of lipoprotein-associated phospholipase A[2] for evaluation in man. Bioorg Med Chem Lett. 2002 Sep 16;12[18] 2603-6.