(S,R,S)-AHPC-PEG2-N3

(S,R,S)-AHPC-PEG2-N3

AT17913

CAS 2010159-45-0

More details

1000 Items

$36.40

$36.40 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $23.80 Total: $119.00
110 $20.16 Total: $201.60
125 $17.08 Total: $427.00
150 $14.56 Total: $728.00
1100 $12.60 Total: $1,260.00

Overview

(S,R,S)-AHPC-PEG2-N3 (VHL Ligand-Linker Conjugates 6) is a synthesized E3 ligase ligand-linker conjugate comprising a (S,R,S)-AHPC-based VHL ligand and a 2-unit PEG linker.

Chemical Properties

Molecular FormulaC28H39N7O6S
Molecular Weight601.72
CAS Numbers2010159-45-0
SolubilityDMSO
Purity98% by HPLC
SMILES CodeC([C@@H](NC(COCCOCCN=[N+]=[N-])=O)[C@](C)(C)C)(=O)N1[C@H](C(NCC2=CC=C(C=C2)C3=C(C)N=CS3)=O)C[C@@H](O)C1

Storage and Handling

0C Short Term, -20C Long Term

References

Gadd MS, et al. Structural basis of PROTAC cooperative recognition for selective protein degradation. Nat Chem Biol. 2017 May;13[5] 514-521.