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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $23.80 | Total: $119.00 |
| 1 | 10 | $20.16 | Total: $201.60 |
| 1 | 25 | $17.08 | Total: $427.00 |
| 1 | 50 | $14.56 | Total: $728.00 |
| 1 | 100 | $12.60 | Total: $1,260.00 |
Overview
YHO-13177 is a potent and specific inhibitor of BCRP, which enhances the cytotoxicity of SN-38 in cancer cells without affecting P-glycoprotein
Chemical Properties
| Molecular Formula | C20H22N2O3S |
| Molecular Weight | 370.47 |
| CAS Numbers | 912287-56-0 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | COc1ccc(cc1OC)C(=Cc1ccc(s1)N1CCC(O)CC1)C#N |
Storage and Handling
0C Short Term, -20C Long Term
References
Yamazaki R, et al. Novel acrylonitrile derivatives, YHO-13177 and YHO-13351, reverse BCRPABCG2-mediated drug resistance in vitro and in vivo. Mol Cancer Ther. 2011 Jul;10[7] 1252-63.