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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $100.30 | Total: $501.50 |
| 1 | 10 | $84.96 | Total: $849.60 |
| 1 | 25 | $71.98 | Total: $1,799.50 |
| 1 | 50 | $61.36 | Total: $3,068.00 |
| 1 | 100 | $53.10 | Total: $5,310.00 |
Overview
PF-04957325 is a potent and selective inhibitor of PDE8.PF-04957325 has an IC50 of 0.7 nM for PDE8A and 0.3 nM for PDE8B.PF-04957325 can be used to study autoimmune encephalomyelitis.
Chemical Properties
| Molecular Formula | C14H15F3N8OS |
| Molecular Weight | 400.38 |
| CAS Numbers | 1305115-80-3 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Nc1nc(nc2n(C[C@H]3CN(Cc4nccs4)CCO3)nnc12)C(F)(F)F |
Storage and Handling
0C Short Term, -20C Long Term
References
Vang AG, et al. Differential Expression and Function of PDE8 and PDE4 in Effector T cells Implications for PDE8 as a Drug Target in Inflammation. Front Pharmacol. 2016 Aug 23;7 259.