Categories
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- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $85.00 | Total: $425.00 |
| 1 | 10 | $72.00 | Total: $720.00 |
| 1 | 25 | $61.00 | Total: $1,525.00 |
| 1 | 50 | $52.00 | Total: $2,600.00 |
| 1 | 100 | $45.00 | Total: $4,500.00 |
Overview
R-10015 is a highly potent and selective LIMK inhibitor that blocks LIMK by binding to the ATP-binding pocket. It inhibits human LIMK1 with an IC50 value of 38 nM. It also exerts broad-spectrum antiviral effects and may be used in HIV infection research.
Chemical Properties
| Molecular Formula | C20H19ClN6O2 |
| Molecular Weight | 410.86 |
| CAS Numbers | 2097938-51-5 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | COC(=O)c1ccc2nc([nH]c2c1)C1CCN(CC1)c1ncnc2[nH]cc(Cl)c12 |
Storage and Handling
0C Short Term, -20C Long Term
References
Yi F, et al. Discovery of Novel Small-Molecule Inhibitors of LIM Domain Kinase for Inhibiting HIV-1. J Virol. 2017 Jun 9;91[13]. pii e02418-16.