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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $39.95 | Total: $199.75 |
| 1 | 10 | $33.84 | Total: $338.40 |
| 1 | 25 | $28.67 | Total: $716.75 |
| 1 | 50 | $24.44 | Total: $1,222.00 |
| 1 | 100 | $21.15 | Total: $2,115.00 |
Overview
Y06137 is an effective and selective BET inhibitor with a Kd of 81 nM for BRD4(1) bromodomain. Y06137 can be used for research on the treatment of castration-resistant prostate cancer.
Chemical Properties
| Molecular Formula | C27H32N4O2 |
| Molecular Weight | 444.57 |
| CAS Numbers | 2226534-49-0 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | C[C@H]1COCCN1c1ccc2nc(-c3ccc4onc(C)c4c3)n(CC3CCCCC3)c2c1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Zhang M, et al. Structure-Based Discovery and Optimization of Benzo[ d]isoxazole Derivatives as Potent and Selective BET Inhibitors for Potential Treatment of Castration-Resistant Prostate Cancer [CRPC]. J Med Chem. 2018 Apr 12;61[7] 3037-3058.