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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $196.35 | Total: $981.75 |
| 1 | 10 | $166.32 | Total: $1,663.20 |
| 1 | 25 | $140.91 | Total: $3,522.75 |
| 1 | 50 | $120.12 | Total: $6,006.00 |
| 1 | 100 | $103.95 | Total: $10,395.00 |
Overview
ZK824190 is an orally available and selective inhibitor of urokinase plasminogen activator (uPA), with IC50 values of 237 nM for uPA, 1600 nM for tPA, and 1850 nM for Plasmin.
Chemical Properties
| Molecular Formula | C22H20F2N2O4 |
| Molecular Weight | 414.4 |
| CAS Numbers | 2254001-81-3 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O(C=1C=C(C=CC1)C2=CC(CN)=CC=C2)C=3N=C(O[C@@H](C(O)=O)CC)C(F)=CC3F |
Storage and Handling
0C Short Term, -20C Long Term
References
Islam I, et al. Discovery of selective urokinase plasminogen activator [uPA] inhibitors as a potential treatment for multiple sclerosis. Bioorg Med Chem Lett. 2018 Nov 1;28[20] 3372-3375.