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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $97.75 | Total: $488.75 |
| 1 | 10 | $82.80 | Total: $828.00 |
| 1 | 25 | $70.15 | Total: $1,753.75 |
| 1 | 50 | $59.80 | Total: $2,990.00 |
| 1 | 100 | $51.75 | Total: $5,175.00 |
Overview
KGA-2727 is a potent and selective SGLT1 inhibitor, with Kis of 97.4 nM and 43.5 nM for human and rat SGLT1, respectively. The selectivity ratios (Ki for SGLT2Ki for SGLT1) of KGA-2727 are 140 (human) and 390 (rat). KGA-2727 for the treatment of diabete.
Chemical Properties
| Molecular Formula | C26H40N4O8 |
| Molecular Weight | 536.62 |
| CAS Numbers | 666842-36-0 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CC(C)c1[nH]nc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c1Cc1ccc(OCCCNCCC(N)=O)cc1C |
Storage and Handling
0C Short Term, -20C Long Term
References
Shibazaki T, et al. KGA-2727, a novel selective inhibitor of a high-affinity sodium glucose cotransporter [SGLT1], exhibits antidiabetic efficacy in rodent models. J Pharmacol Exp Ther. 2012 Aug;342[2] 288-96.