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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $31.45 | Total: $157.25 |
| 1 | 10 | $26.64 | Total: $266.40 |
| 1 | 25 | $22.57 | Total: $564.25 |
| 1 | 50 | $19.24 | Total: $962.00 |
| 1 | 100 | $16.65 | Total: $1,665.00 |
Overview
R-268712 is a specific activin receptor-like kinase 5 (ALK5) inhibitor(IC50 of 2.5 nM). It is also an orally active transforming growth factor-? type I receptor inhibitor.
Chemical Properties
| Molecular Formula | C20H18FN5O |
| Molecular Weight | 363.39 |
| CAS Numbers | 879487-87-3 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cc1cccc(n1)-c1n[nH]cc1-c1ccc(F)c(c1)-c1cnn(CCO)c1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Terashima H, et al. R-268712, an orally active transforming growth factor-? type I receptor inhibitor, prevents glomerular sclerosis in a Thy1 nephritis model. Eur J Pharmacol. 2014 Jul 5;734 60-6.