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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $31.45 | Total: $157.25 |
| 1 | 10 | $26.64 | Total: $266.40 |
| 1 | 25 | $22.57 | Total: $564.25 |
| 1 | 50 | $19.24 | Total: $962.00 |
| 1 | 100 | $16.65 | Total: $1,665.00 |
Overview
TM-N1324 is a GPR39 agonist. TM-N1324 activates human GPR39 with high efficacy and potencies of 280 nM and 9 nM in the absence and presence of Zn2+, respectively. TM-N1324 has similar potencies to murine GPR39 with EC50s of 180 nM and 5 nM, respectively.
Chemical Properties
| Molecular Formula | C18H13ClFN7O |
| Molecular Weight | 397.79 |
| CAS Numbers | 1144477-35-9 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cc1nn(c2NC(=O)CC(c12)c1ccc(F)cc1Cl)-c1ncnc2[nH]cnc12 |
Storage and Handling
0C Short Term, -20C Long Term
References
Frimurer TM, et al. Model-Based Discovery of Synthetic Agonists for the Zn2+-Sensing G-Protein-Coupled Receptor 39 [GPR39] Reveals Novel Biological Functions. J Med Chem. 2017 Feb 9;60[3] 886-898.