N-Acetyl lysyltyrosylcysteine amide

N-Acetyl lysyltyrosylcysteine amide

AT38063

CAS 1287585-40-3

More details

1000 Items

$79.30

$79.30 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $51.85 Total: $259.25
110 $43.92 Total: $439.20
125 $37.21 Total: $930.25
150 $31.72 Total: $1,586.00
1100 $27.45 Total: $2,745.00

Overview

N-Acetyl lysyltyrosylcysteine amide is a non-toxic, potent, reversible, and specific myeloperoxidase (MPO) tripeptide inhibitor that effectively inhibits MPO production in vivo, attenuates neuronal damage, preserves brain tissue and neurological function post-stroke, and inhibits MPO-dependent hypochlorite (HOCl) production, protein nitration, and LDL oxidation. It is also used in the study of bronchial dysplasia.

Chemical Properties

Molecular FormulaC20H31N5O5S
Molecular Weight453.56
CAS Numbers1287585-40-3
SolubilityDMSO
Purity98% by HPLC
SMILES Code[C@@H](CC1=CC=C(O)C=C1)(NC([C@H](CCCCN)NC(C)=O)=O)C(N[C@H](C(N)=O)CS)=O

Storage and Handling

0C Short Term, -20C Long Term

References

Yu G, et al. Inhibition of myeloperoxidase oxidant production by N-acetyl lysyltyrosylcysteine amide reduces brain damage in a murine model of stroke [published correction appears in J Neuroinflammation. 2016;13[1] 166]. J Neuroinflammation. 2016;13[1] 119. Published 2016 May 24.