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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $22.10 | Total: $110.50 |
| 1 | 10 | $18.72 | Total: $187.20 |
| 1 | 25 | $15.86 | Total: $396.50 |
| 1 | 50 | $13.52 | Total: $676.00 |
| 1 | 100 | $11.70 | Total: $1,170.00 |
Overview
NAMPT Activator-1 (compound 1) is an effective and specific activator of niacinamide phosphotransferase (Compound 1) with a wide range of EC50 (3.3-3.7 ?M). NAMPT activator-1 effectively protects cultured cells from FK866-mediated toxicity and is a potential neuroprotective compound.
Chemical Properties
| Molecular Formula | C16H17N3O3 |
| Molecular Weight | 299.32 |
| CAS Numbers | 701929-65-9 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CCOC(=O)c1ccc(NC(=O)NCc2ccncc2)cc1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Akiu M, et al. Discovery of 1-[2-[1-methyl-1H-pyrazol-5-yl]-[1, 2, 4] triazolo [1, 5-a] pyridin-6-yl]-3-[pyridin-4-ylmethyl] urea as a potent NAMPT [nicotinamide phosphoribosyltransferase] activator with attenuated CYP inhibition. Bioorganic & Medicinal Chemistry Letters. 2021;43 128048.