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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $141.10 | Total: $705.50 |
| 1 | 10 | $119.52 | Total: $1,195.20 |
| 1 | 25 | $101.26 | Total: $2,531.50 |
| 1 | 50 | $86.32 | Total: $4,316.00 |
| 1 | 100 | $74.70 | Total: $7,470.00 |
Overview
KW-2450 Formate is an IGF-1RIR tyrosine kinase inhibitor with antitumor effects that acts through inhibition of Aurora A and B kinases.KW-2450 Formate inhibits the growth of TNBC xenografts and induces tetraploid accumulation.
Chemical Properties
| Molecular Formula | C29H31N5O5S |
| Molecular Weight | 561.65 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O=C(C1=C(C)C=CS1)NC(C=C(C=C2)CN3CCN(CC3)C(CO)=O)=C2C=CC4=NNC5=CC=CC=C45.[H]C(O)=O |
Storage and Handling
0C Short Term, -20C Long Term
References
Kai K, et al. Antitumor Activity of KW-2450 against Triple-Negative Breast Cancer by Inhibiting Aurora A and B Kinases. Mol Cancer Ther. 2015 Dec;14[12] 2687-99.