BIRM 271

BIRM 271

AT77638

CAS 149106-77-4

More details

1000 Items

$215.80

$215.80 per mg

Quantity Discount Table - Order More To Get More Price Discount

QuantitymgUnit Price ($/mg or $/Unit)Final Price
15 $141.10 Total: $705.50
110 $119.52 Total: $1,195.20
125 $101.26 Total: $2,531.50
150 $86.32 Total: $4,316.00
1100 $74.70 Total: $7,470.00

Overview

BIRM 271 is a novel arachidonic acid release inhibitor that blocks leukotriene B4 and platelet-activating factor biosynthesis in human neutrophils. BIRM 271 and BIRM 270 are enantiomers that inhibit the production of leukotriene B4 with IC50 of 40 nM.

Chemical Properties

Molecular FormulaC21H25N3O
Molecular Weight335.44
CAS Numbers149106-77-4
SolubilityDMSO
Purity98% by HPLC
SMILES CodeN([C@H](CC1CCCCC1)C2=CC=CC=N2)C=3OC=4C(N3)=CC(C)=CC4

Storage and Handling

0C Short Term, -20C Long Term

References

Farina PR, et al. BIRM 270 a novel inhibitor of arachidonate release that blocks leukotriene B4 and platelet-activating factor biosynthesis in human neutrophils. J Pharmacol Exp Ther. 1994;271[3] 1418-1426.