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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $57.80 | Total: $289.00 |
| 1 | 10 | $48.96 | Total: $489.60 |
| 1 | 25 | $41.48 | Total: $1,037.00 |
| 1 | 50 | $35.36 | Total: $1,768.00 |
| 1 | 100 | $30.60 | Total: $3,060.00 |
Overview
K-Ras-PDE?-IN-1 is a potent inhibitor of competitive K-Ras-PDE? that binds to the farnesyl binding pocket of PDE? (Kd of 8 nM).
Chemical Properties
| Molecular Formula | C25H26FN5O2 |
| Molecular Weight | 447.5 |
| CAS Numbers | 1841464-21-8 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cc1ccc(cc1)-n1cc2c(C)nn(CCCC(=O)NCCc3ccc(F)cc3)c(=O)c2n1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Sandip Murarka, et al. Development of Pyridazinone Chemotypes Targeting the PDE? Prenyl Binding Site. Chemistry. 2017 May 2;23[25] 6083-6093.