Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
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- Customized Screening Library
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- SARS-CoV
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $57.80 | Total: $289.00 |
| 1 | 10 | $48.96 | Total: $489.60 |
| 1 | 25 | $41.48 | Total: $1,037.00 |
| 1 | 50 | $35.36 | Total: $1,768.00 |
| 1 | 100 | $30.60 | Total: $3,060.00 |
Overview
BMS-986260 is a selective, and orally bioavailable TGF?R1 inhibitor(IC50 = 1.6 nM).
Chemical Properties
| Molecular Formula | C18H12ClFN6O |
| Molecular Weight | 382.78 |
| CAS Numbers | 2001559-19-7 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | C(CO)N1C(=C(N=C1)C2=CC(Cl)=C(F)C=C2)C3=NN4C(C=C3)=NC=C4C#N |
Storage and Handling
0C Short Term, -20C Long Term
References
Discovery of BMS-986260, a Potent, Selective, and Orally Bioavailable TGF?R1 Inhibitor as an Immuno-oncology Agent[J]. ACS Medicinal Chemistry Letters, 2020, 11[2] 172-178.