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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $80.75 | Total: $403.75 |
| 1 | 10 | $68.40 | Total: $684.00 |
| 1 | 25 | $57.95 | Total: $1,448.75 |
| 1 | 50 | $49.40 | Total: $2,470.00 |
| 1 | 100 | $42.75 | Total: $4,275.00 |
Overview
BI-0115 is a selective small molecule inhibitor of LOX-1 that blocks cellular uptake of oxLDL. It binding triggers receptor inhibition by formation of dimers of the homodimeric ligand binding domain. The structure of LOX-1 bound to BI-0115 shows that inter-ligand interactions at the receptor interfaces are key to the formation of the receptor tetramer thereby blocking oxLDL binding.
Chemical Properties
| Molecular Formula | C15H14ClN3O |
| Molecular Weight | 287.74 |
| CAS Numbers | 4929-23-1 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CCCN1c2cccnc2Nc2cc(Cl)ccc2C1=O |
Storage and Handling
0C Short Term, -20C Long Term