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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $36.55 | Total: $182.75 |
| 1 | 10 | $30.96 | Total: $309.60 |
| 1 | 25 | $26.23 | Total: $655.75 |
| 1 | 50 | $22.36 | Total: $1,118.00 |
| 1 | 100 | $19.35 | Total: $1,935.00 |
Overview
M435-1279 is a UBE2T inhibitor that blocks UBE2T-mediated degradation of RACK1, thereby inhibiting the hyperactivation of the Wnt?-catenin signaling pathway.
Chemical Properties
| Molecular Formula | C18H17N3O5S2 |
| Molecular Weight | 419.47 |
| CAS Numbers | 1359431-16-5 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | NS(=O)(=O)c1ccc(NC(=O)c2c(O)c3c4CCCCc4sc3[nH]c2=O)cc1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Yu Z, Jiang X, Qin L, Deng H, Wang J, Ren W, Li H, Zhao L, Liu H, Yan H, Shi W, Wang Q, Luo C, Long B, Zhou H, Sun H, Jiao Z. A novel UBE2T inhibitor suppresses Wnt?-catenin signaling hyperactivation and gastric cancer progression by blocking RACK1 ubiquitination. Oncogene. 2021 Feb;40[5] 1027-1042. doi 10.1038s41388-020-01572-w. Epub 2020 Dec 15. Erratum in Oncogene. 2021 Apr;40[14] 2622-2623. PMID 33323973; PMCID PMC7862066.