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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $85.00 | Total: $425.00 |
| 1 | 10 | $72.00 | Total: $720.00 |
| 1 | 25 | $61.00 | Total: $1,525.00 |
| 1 | 50 | $52.00 | Total: $2,600.00 |
| 1 | 100 | $45.00 | Total: $4,500.00 |
Overview
IRE1? kinase-IN-1 is a highly selective IRE1? (ERN1) inhibitor, with an IC50 of 77 nM, displaying 100-fold selectivity over the IRE1? isoform. It inhibits ER stress-induced IRE1? oligomerization and autophosphorylation, as well as IRE1? RNase activity (IC50=80 nM).
Chemical Properties
| Molecular Formula | C26H26ClFN8 |
| Molecular Weight | 504.99 |
| CAS Numbers | 2328097-41-0 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CN1CCC(CNc2cc(Cl)nn3c(cnc23)-c2cc3nc(Nc4ccccc4)[nH]c3cc2F)CC1 |
Storage and Handling
0C Short Term, -20C Long Term