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TAK-924 (MLN4924 , Pevonedistat)
AOB87174
CAS: 905579-51-3
Chemical Name: Pevonedistat; QCR-143; [(1S,2S,4R)-4-[4-[[(1S)-2,3-Dihydro-1H-inden-1-yl]amino]pyrrolo[2,3-d]pyrimidin-7-yl]-2-hydroxycyclopentyl]methyl sulfamate
487 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $22.95 | Total: $114.75 |
| 1 | 10 | $19.44 | Total: $194.40 |
| 1 | 25 | $16.47 | Total: $411.75 |
| 1 | 50 | $14.04 | Total: $702.00 |
| 1 | 100 | $12.15 | Total: $1,215.00 |
Overview
Novel inhibitor of CRL E3s, inhibiting the formation of Kras(G12D)-induced lung tumors through a similar mechanism involving inactivation of NF-κB and mTOR and accumulation of tumor suppressor substrates
Chemical Properties
| Molecular Formula | C21H25N5O4S |
| Molecular Weight | 443.52 |
| CAS Numbers | 905579-51-3 |
| Solubility | DMSO |
| Purity | 99% (HPLC) |
Storage and Handling
0°C (short term), -20°C (long term), desiccated
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