33DFTG (TD139)

Name: 33DFTG (TD139)
Brand: AOBIOUS
SKU: AOB37408
Price: 25 USD
Availability: InStock

Cat No: AOB37408

Condition

CAS No: 1450824-22-2

AOBIOUS launched this product in 2017

CITATIONS - Publications That Use AOBIOUS Product

1) Genetic knockout and pharmacological inhibition (2022)

More details

141 Item Items

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Quantity Discount Table - Order More To Get More Price Discount

Quantity	mg	Unit Price ($/mg or $/Unit)	Final Price
1	5	$21.25	Total: $106.25
1	10	$18.00	Total: $180.00
1	25	$15.25	Total: $381.25
1	50	$13.00	Total: $650.00
1	100	$11.25	Total: $1,125.00

Overview

Novel galectin-3 inhibitor, reducing both pathological corneal neovascularization and fibrosis

Chemical Properties

Molecular Formula	C28H30F2N6O8S
Molecular Weight	648.64
CAS Numbers	1450824-22-2
Solubility	DMSO
Purity	98% by HPLC
IUPAC/Chemical Name	(2R,2'R,3R,3'R,4S,4'S,5R,5'R,6S,6'S)-6,6'-thiobis(4-(4-(3-fluorophenyl)-1H-1,2,3-triazol-1-yl)-2-(hydroxymethyl)tetrahydro-2H-pyran-3,5-diol)
InChl Key	YGIDGBAHDZEYMT-MQFIMZJJSA-N
InChl Code	InChI=1S/C28H30F2N6O8S/c29-15-5-1-3-13(7-15)17-9-35(33-31-17)21-23(39)19(11-37)43-27(25(21)41)45-28-26(42)22(24(40)20(12-38)44-28)36-10-18(32-34-36)14-4-2-6-16(30)8-14/h1-10,19-28,37-42H,11-12H2/t19-,20-,21+,22+,23+,24+,25-,26-,27+,28+/m1/s1
SMILES Code	O[C@H]([C@@H](N1N=NC(C2=CC=CC(F)=C2)=C1)[C@H]([C@@H](CO)O3)O)[C@@H]3S[C@H]4[C@@H]([C@@H](N5N=NC(C6=CC=CC(F)=C6)=C5)[C@H]([C@@H](CO)O4)O)O

Storage and Handling

0°C (short term), -20°C (long term), desiccated

Synonyms

TD-139; TD139; TD 139

References

1) Wu SY, Huang JH, Chen WY, Chan YC, Lin CH, Chen YC, Liu FT, Wu-Hsieh BA. Cell Intrinsic Galectin-3 Attenuates Neutrophil ROS-Dependent Killing of Candida by Modulating CR3 Downstream Syk Activation. Front Immunol. 2017 Feb 3;8:48. doi: 10.3389/fimmu.2017.00048. PubMed PMID: 28217127; PubMed Central PMCID: PMC5289966.

2) Saksida T, Nikolic I, Vujicic M, Nilsson UJ, Leffler H, Lukic ML, Stojanovic I, Stosic-Grujicic S. Galectin-3 deficiency protects pancreatic islet cells from cytokine-triggered apoptosis in vitro. J Cell Physiol. 2013 Jul;228(7):1568-76. doi: 10.1002/jcp.24318. PubMed PMID: 23280610.