Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
- Chemokines
- Cytokine Receptors
- Biomarkers and Buffer Solutions
- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
- Apoptosis
- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
- ELISA KIT
- Natural Products
- Lab Equipments
- Humanized Mice for PDX Platform
- Rare Chemicals
- Custom Synthesis
- Antibacterial
- Antifungal
- Antioxidant
- Antiviral
- Molecular Glues
- SARS-CoV
IWP-O1
AOBS1962
CAS No: 2074607-48-8
Chemical Name: 5-Phenyl-N-(5-phenylpyridin-2-yl)-4-(pyridin-4-yl)-1H-1,2,3-triazol-1-acetamide
1000 Items
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $31.02 | Total: $155.12 |
| 1 | 10 | $26.28 | Total: $262.80 |
| 1 | 25 | $22.27 | Total: $556.63 |
| 1 | 50 | $18.98 | Total: $949.00 |
| 1 | 100 | $16.43 | Total: $1,642.50 |
Overview
An inhibitor of Porcupine (Porcn), an acyl (palmitoyl) transferase essential for secretion of Wnt proteins and involved in both embryonic development and tumor progression. IWP-O1 has good metabolic stability and is extremely potent, exhibiting an EC50 value of 80 pM in a cultured cell reporter assay of Wnt signaling.
Chemical Properties
| Molecular Formula | C26H20N6O |
| Molecular Weight | 432.48 |
| CAS Numbers | 2074607-48-8 |
| Solubility | DMSA: 25 mg/mL |
| Purity | 98% by HPLC |
Storage and Handling
0°C (short term), -20°C (long term), desiccated