Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
- Chemokines
- Cytokine Receptors
- Biomarkers and Buffer Solutions
- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
- Apoptosis
- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
- ELISA KIT
- Natural Products
- Lab Equipments
- Humanized Mice for PDX Platform
- Rare Chemicals
- Custom Synthesis
- Antibacterial
- Antifungal
- Antioxidant
- Antiviral
- Molecular Glues
- SARS-CoV
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $24.65 | Total: $123.25 |
| 1 | 10 | $20.88 | Total: $208.80 |
| 1 | 25 | $17.69 | Total: $442.25 |
| 1 | 50 | $15.08 | Total: $754.00 |
| 1 | 100 | $13.05 | Total: $1,305.00 |
Overview
FL-411 (BRD4-IN-1) is a potent and selective BRD4 inhibitor with an IC50 of 0.43
Chemical Properties
| Molecular Formula | C18H19N3O2S |
| Molecular Weight | 341.43 |
| CAS Numbers | 2118944-88-8 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CN1CCc2c(C1)sc1[nH]c(nc(=O)c21)-c1cc(C)c(O)c(C)c1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Ouyang L,etal.Discovery of a Small-Molecule Bromodomain-Containing Protein 4 [BRD4] Inhibitor That Induces AMP-Activated Protein Kinase-Modulated Autophagy-Associated Cell Death in Breast Cancer.J Med Chem. 2017 Dec 28;60[24] 9990-10012.