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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $22.95 | Total: $114.75 |
| 1 | 10 | $19.44 | Total: $194.40 |
| 1 | 25 | $16.47 | Total: $411.75 |
| 1 | 50 | $14.04 | Total: $702.00 |
| 1 | 100 | $12.15 | Total: $1,215.00 |
Overview
GW6471 is an antagonist of PPAR? with IC50 of 0.24 ? M. GW6471 enhances the binding affinity of the PPAR ? ligand-binding domain to the co-repressor proteins SMRT and NCoR.
Chemical Properties
| Molecular Formula | C35H36F3N3O4 |
| Molecular Weight | 619.67 |
| CAS Numbers | 880635-03-0 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CCC(=O)NC[C@H](Cc1ccc(OCCc2nc(oc2C)-c2ccccc2)cc1)NC(C)=CC(=O)c1ccc(cc1)C(F)(F)F |
Storage and Handling
0C Short Term, -20C Long Term
References
Abu Aboud O, et al. Inhibition of PPAR? induces cell cycle arrest and apoptosis, and synergizes with glycolysis inhibition in kidney cancer cells. PLoS One. 2013 Aug 7;8[8] e71115.