Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
- Chemokines
- Cytokine Receptors
- Biomarkers and Buffer Solutions
- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
- Apoptosis
- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
- ELISA KIT
- Natural Products
- Lab Equipments
- Humanized Mice for PDX Platform
- Rare Chemicals
- Custom Synthesis
- Antibacterial
- Antifungal
- Antioxidant
- Antiviral
- Molecular Glues
- SARS-CoV
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $34.85 | Total: $174.25 |
| 1 | 10 | $29.52 | Total: $295.20 |
| 1 | 25 | $25.01 | Total: $625.25 |
| 1 | 50 | $21.32 | Total: $1,066.00 |
| 1 | 100 | $18.45 | Total: $1,845.00 |
Overview
SR1664 is a potent and selective PPAR? inhibitor with potential antidiabetic activity. SR1664 binds to PPAR? and potently inhibits Cdk5-mediated PPAR? phosphorylation (IC50 = 80 nM; Ki = 28.67 nM) without exhibiting PPAR? agonist activity.
Chemical Properties
| Molecular Formula | C33H29N3O5 |
| Molecular Weight | 547.6 |
| CAS Numbers | 1338259-05-4 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | C[C@H](NC(=O)c1ccc2n(Cc3ccc(cc3)-c3ccccc3C(O)=O)c(C)c(C)c2c1)c1ccc(cc1)[N+]([O-])=O |
Storage and Handling
0C Short Term, -20C Long Term
References
Marciano DP, Kuruvilla DS, Boregowda SV, et al. Pharmacological repression of PPAR? promotes osteogenesis. Nat Commun. 2015;6 7443. Published 2015 Jun 12.