Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
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- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $22.10 | Total: $110.50 |
| 1 | 10 | $18.72 | Total: $187.20 |
| 1 | 25 | $15.86 | Total: $396.50 |
| 1 | 50 | $13.52 | Total: $676.00 |
| 1 | 100 | $11.70 | Total: $1,170.00 |
Overview
SR 16832 is a dual-site PPAR? inhibitor. It also inhibits the binding of endogenous ligands and transcriptional activity of PPAR?, more effectively than the orthosteric covalent antagonist GW 9662 and T 0070907.
Chemical Properties
| Molecular Formula | C17H12ClN3O4 |
| Molecular Weight | 357.75 |
| CAS Numbers | 2088135-12-8 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | N(C(=O)C1=CC(N(=O)=O)=CC=C1Cl)C=2C3=C(C=CC(OC)=C3)N=CC2 |
Storage and Handling
0C Short Term, -20C Long Term
References
Brust et al [2017] Modification of the othosteric PPAR? covalent antagonist scaffold yields an improved dual-site allosteric inhibitor. ACS Chem.Biol. 12 969