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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $349.35 | Total: $1,746.75 |
| 1 | 10 | $295.92 | Total: $2,959.20 |
| 1 | 25 | $250.71 | Total: $6,267.75 |
| 1 | 50 | $213.72 | Total: $10,686.00 |
| 1 | 100 | $184.95 | Total: $18,495.01 |
Overview
BY27, a potent and selective BET BD2 inhibitor (Ki: 3.1 nM) with anticancer activity, inhibits BD1BD2 of BRD2, BRD3, BRD4, and BRDT, and suppresses tumor growth.
Chemical Properties
| Molecular Formula | C22H21ClN6 |
| Molecular Weight | 404.89 |
| CAS Numbers | 2247236-59-3 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | N([C@H]1C=2C(N3C(CC1)=NN=C3C)=CC=C(C2)C=4C=NN(C)C4)C5=CC=C(Cl)C=C5 |
Storage and Handling
0C Short Term, -20C Long Term
References
Chen D, et al. Discovery, structural insight, and bioactivities of BY27 as a selective inhibitor of the second bromodomains of BET proteins. Eur J Med Chem. 2019 Aug 21;182 111633.