Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
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- Molecular Probes
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- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $64.60 | Total: $323.00 |
| 1 | 10 | $54.72 | Total: $547.20 |
| 1 | 25 | $46.36 | Total: $1,159.00 |
| 1 | 50 | $39.52 | Total: $1,976.00 |
| 1 | 100 | $34.20 | Total: $3,420.00 |
Overview
DW14800 is an inhibitor of PRMT5 (IC50 = 17 nM), enhances the transcription of HNF4?, and reduces the level of H4R3me2s.
Chemical Properties
| Molecular Formula | C31H36N4O3 |
| Molecular Weight | 512.64 |
| CAS Numbers | 2243709-60-4 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | C(=O)(N1CC=2C(=CC(C(NCC(CN3CC=4C(CC3)=CC=CC4)O)=O)=CC2)CC1)C5=CC=C(N(C)C)C=C5 |
Storage and Handling
0C Short Term, -20C Long Term
References
Zheng BN, et al. Targeting PRMT5 Activity Inhibits the Malignancy of Hepatocellular Carcinoma by Promoting the Transcription of HNF4?. Theranostics. 2019 Apr 13;9[9] 2606-2617.