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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $122.40 | Total: $612.00 |
| 1 | 10 | $103.68 | Total: $1,036.80 |
| 1 | 25 | $87.84 | Total: $2,196.00 |
| 1 | 50 | $74.88 | Total: $3,744.00 |
| 1 | 100 | $64.80 | Total: $6,480.00 |
Overview
M-89, a highly potent and specific inhibitor of the menin-mixed lineage leukemia (Menin-MLL) protein-protein interaction, exhibits a Kd of 1.4 nM for menin binding. This compound holds potential for treating MLL leukemia.
Chemical Properties
| Molecular Formula | C37H47N5O4S |
| Molecular Weight | 657.87 |
| CAS Numbers | 2363165-42-6 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CNC(=O)O[C@H]1CCC[C@@H]1[C@@]1(CN(C)Cc2ccccc12)C1CCN(CC2CN(C2)c2ccc(cc2)S(=O)(=O)c2ccncc2)CC1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Aguilar A, et al. Structure-Based Discovery of M-89 as a Highly Potent Inhibitor of the Menin-Mixed Lineage Leukemia [Menin-MLL] Protein-Protein Interaction. J Med Chem. 2019 Jul 11;62[13] 6015-6034.