Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
- Chemokines
- Cytokine Receptors
- Biomarkers and Buffer Solutions
- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
- Apoptosis
- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
- ELISA KIT
- Natural Products
- Lab Equipments
- Humanized Mice for PDX Platform
- Rare Chemicals
- Custom Synthesis
- Antibacterial
- Antifungal
- Antioxidant
- Antiviral
- Molecular Glues
- SARS-CoV
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $90.10 | Total: $450.50 |
| 1 | 10 | $76.32 | Total: $763.20 |
| 1 | 25 | $64.66 | Total: $1,616.50 |
| 1 | 50 | $55.12 | Total: $2,756.00 |
| 1 | 100 | $47.70 | Total: $4,770.00 |
Overview
PROTAC BRD4 ligand-1, a component of Protac GNE-987, is a ligand for BRD4 and acts as an inhibitor of BET.
Chemical Properties
| Molecular Formula | C23H18F2N4O5S |
| Molecular Weight | 500.47 |
| CAS Numbers | 2313230-51-0 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cn1cc2-c3cc(CS(C)(=O)=O)c(cc3N(Cc3c[nH]c(c23)c1=O)c1ncc(F)cc1F)C(O)=O |
Storage and Handling
0C Short Term, -20C Long Term
References
Pillow TH, et al. Antibody Conjugation of a Chimeric BET Degrader Enables in vivo Activity. ChemMedChem. 2019 Oct 31.