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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $56.95 | Total: $284.75 |
| 1 | 10 | $48.24 | Total: $482.40 |
| 1 | 25 | $40.87 | Total: $1,021.75 |
| 1 | 50 | $34.84 | Total: $1,742.00 |
| 1 | 100 | $30.15 | Total: $3,015.00 |
Overview
ZEN-3219 is a BET inhibitor, which has inhibitory effect on BRD4(BD1), BRD4(BD2) and BRD4(BD1BD2). ZEN-3219 has inhibitory effect on BRD4(BD1), The IC50 values of BRD4(BD2) and BRD4(BD1BD2) were 0.48, 0.16 and 0.47 ?M, respectively. ZEN-3219 is a component of PROTAC molecule and can induce BRD4 degradation.
Chemical Properties
| Molecular Formula | C19H18N2O3 |
| Molecular Weight | 322.36 |
| CAS Numbers | 1952264-34-4 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CC=1C(C2=CN(CC3=CC=C(C=C3)C4CO4)C(=O)C=C2)=C(C)ON1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Kharenko OA, et al. Design and Characterization of Novel Covalent Bromodomain and Extra-Terminal Domain [BET] Inhibitors Targeting a Methionine. J Med Chem. 2018;61[18] 8202-8211.