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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $97.75 | Total: $488.75 |
| 1 | 10 | $82.80 | Total: $828.00 |
| 1 | 25 | $70.15 | Total: $1,753.75 |
| 1 | 50 | $59.80 | Total: $2,990.00 |
| 1 | 100 | $51.75 | Total: $5,175.00 |
Overview
UNC6852 contains an EED ligand (IC50 = 247 nM) and a von Hippel-Lindau ligand and is a selective polycomb repressive complex 2 (PRC2) degrader based on PROTAC.
Chemical Properties
| Molecular Formula | C43H48N10O6S |
| Molecular Weight | 832.97 |
| CAS Numbers | 2688842-08-0 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cc1ncsc1-c1ccc(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)CCCNC(=O)c2ccc(cc2)-c2cnc(NCc3ccco3)n3cnnc23)C(C)(C)C)cc1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Potjewyd F, et al. Degradation of Polycomb Repressive Complex 2 with an EED-Targeted Bivalent Chemical Degrader. Cell Chem Biol. 2020 Jan 16;27[1] 47-56.e15.