Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
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- Customized Screening Library
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- Primary Cells
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $43.35 | Total: $216.75 |
| 1 | 10 | $36.72 | Total: $367.20 |
| 1 | 25 | $31.11 | Total: $777.75 |
| 1 | 50 | $26.52 | Total: $1,326.00 |
| 1 | 100 | $22.95 | Total: $2,295.00 |
Overview
EBI-2511 is a highly potent, orally active inhibitor of EZH2, with an IC50 of 6 nM in Pfeffiera cell lines.
Chemical Properties
| Molecular Formula | C34H48N4O4 |
| Molecular Weight | 576.77 |
| CAS Numbers | 2098546-05-3 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CCN(C1CCOCC1)c1cc2oc(cc2c(C(=O)NCc2c(C)cc(C)[nH]c2=O)c1CC)C1CCN(CC1)C(C)C |
Storage and Handling
0C Short Term, -20C Long Term
References
Lu B, et al. Discovery of EBI-2511 A Highly Potent and Orally Active EZH2 Inhibitor for the Treatment of Non-Hodgkin's Lymphoma. ACS Med Chem Lett. 2018 Jan 29;9[2] 98-102.