Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $27.20 | Total: $136.00 |
| 1 | 10 | $23.04 | Total: $230.40 |
| 1 | 25 | $19.52 | Total: $488.00 |
| 1 | 50 | $16.64 | Total: $832.00 |
| 1 | 100 | $14.40 | Total: $1,440.00 |
Overview
EML 425 is a potent and selective inhibitor of CREB binding protein (CBP)p300 (IC50s: 2.9 and 1.1 ?M, respectively).
Chemical Properties
| Molecular Formula | C27H24N2O4 |
| Molecular Weight | 440.49 |
| CAS Numbers | 1675821-32-5 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cc1cc(O)cc(C)c1C=C1C(=O)N(Cc2ccccc2)C(=O)N(Cc2ccccc2)C1=O |
Storage and Handling
0C Short Term, -20C Long Term
References
Milite C, et al. A novel cell-permeable, selective, and noncompetitive inhibitor of KAT3 histone acetyltransferases from a combined molecular pruningclassical isosterism approach. J Med Chem. 2015 Mar 26;58[6] 2779-98.