Categories
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- Protein Control Ligand
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- Function Modulators
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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $28.05 | Total: $140.25 |
| 1 | 10 | $23.76 | Total: $237.60 |
| 1 | 25 | $20.13 | Total: $503.25 |
| 1 | 50 | $17.16 | Total: $858.00 |
| 1 | 100 | $14.85 | Total: $1,485.00 |
Overview
UNC0321 is an effective inhibitor of histone methyltransferase G9a with a Ki of 63 pM and with IC50s 9 nM and 6 nM in ECSD and CLOT assays. UNC0321 inhibits GLP with IC50s of 15 nM and 23 nM in ECSD and CLOT assays.
Chemical Properties
| Molecular Formula | C27H45N7O3 |
| Molecular Weight | 515.69 |
| CAS Numbers | 1238673-32-9 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | COc1cc2c(NC3CCN(C)CC3)nc(nc2cc1OCCOCCN(C)C)N1CCCN(C)CC1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Liu F, et al. Protein lysine methyltransferase G9a inhibitors design, synthesis, and structure activity relationships of 2,4-diamino-7-aminoalkoxy-quinazolines. J Med Chem. 2010 Aug 12;53[15] 5844-57.