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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $22.95 | Total: $114.75 |
| 1 | 10 | $19.44 | Total: $194.40 |
| 1 | 25 | $16.47 | Total: $411.75 |
| 1 | 50 | $14.04 | Total: $702.00 |
| 1 | 100 | $12.15 | Total: $1,215.00 |
Overview
(R)-(-)-JQ1 Enantiomer is the stereoisomer of (+)-JQ1, a BET bromodomain inhibitor, which acts on BRD4(12) with IC50 values of 77 nM and 33 nM in a cell-free assay.
Chemical Properties
| Molecular Formula | C23H25ClN4O2S |
| Molecular Weight | 456.99 |
| CAS Numbers | 1268524-71-5 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | Cc1nnc2[C@@H](CC(=O)OC(C)(C)C)N=C(c3c(C)c(C)sc3-n12)c1ccc(Cl)cc1 |
Storage and Handling
0C Short Term, -20C Long Term
References
Mahe M, et al. An FGFR3MYC positive feedback loop provides new opportunities for targeted therapies in bladder cancers. EMBO Mol Med. 2018 Apr;10[4]. pii e8163.