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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $79.90 | Total: $399.50 |
| 1 | 10 | $67.68 | Total: $676.80 |
| 1 | 25 | $57.34 | Total: $1,433.50 |
| 1 | 50 | $48.88 | Total: $2,444.00 |
| 1 | 100 | $42.30 | Total: $4,230.00 |
Overview
SW2_110A is a cell-permeable, selective chromosome group 8 chromosome domain (CBX8 ChD) inhibitor with a Kd of 800 nM. In vitro, SW2_110A is 5-fold more selective for CBX8 ChD than all other CBX enantiomers.
Chemical Properties
| Molecular Formula | C42H60N6O7 |
| Molecular Weight | 760.96 |
| CAS Numbers | 2579696-95-8 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | [C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC#C)=O)CO)=O)CCCCN(CC)CC)=O)[C@@H](CC)C)=O)(NC(=O)C1=CC=C(OC2=CC=CC=C2)C=C1)[C@H]3CCCC3 |
Storage and Handling
0C Short Term, -20C Long Term
References
Wang S, et al. Optimization of Ligands Using Focused DNA-Encoded Libraries To Develop a Selective, Cell-Permeable CBX8 Chromodomain Inhibitor. ACS Chem Biol. 2020;15[1] 112-13