Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
- Chemokines
- Cytokine Receptors
- Biomarkers and Buffer Solutions
- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
- Apoptosis
- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
- ELISA KIT
- Natural Products
- Lab Equipments
- Humanized Mice for PDX Platform
- Rare Chemicals
- Custom Synthesis
- Antibacterial
- Antifungal
- Antioxidant
- Antiviral
- Molecular Glues
- SARS-CoV
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $287.30 | Total: $1,436.50 |
| 1 | 10 | $243.36 | Total: $2,433.60 |
| 1 | 25 | $206.18 | Total: $5,154.50 |
| 1 | 50 | $175.76 | Total: $8,788.00 |
| 1 | 100 | $152.10 | Total: $15,210.01 |
Overview
MRTX-1719 is a potent, first-in-class, selective inhibitor of the PRMT5MTA complex, with an IC50 of less than 10 nM in PRMT5MTA MTAP DEL SDMA cells.
Chemical Properties
| Molecular Formula | C23H18ClFN6O2 |
| Molecular Weight | 464.88 |
| CAS Numbers | 2630904-45-7 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CN1C(=C(C=N1)C=2C=C3C(=CC2)C(=O)NN=C3CN)C4=C(C#N)C(OC5CC5)=CC(Cl)=C4F |
Storage and Handling
0C Short Term, -20C Long Term
References
Targeting the genetic and immunological drivers of cancer.