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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $84.15 | Total: $420.75 |
| 1 | 10 | $71.28 | Total: $712.80 |
| 1 | 25 | $60.39 | Total: $1,509.75 |
| 1 | 50 | $51.48 | Total: $2,574.00 |
| 1 | 100 | $44.55 | Total: $4,455.00 |
Overview
PBRM1-BD2-IN-7, a selective and cell-active inhibitor targeting the polybromo-1 (PBRM1) bromodomain, demonstrates inhibitory efficacy against PBRM1-BD2 with an IC50 value of 0.29 ?M. This compound is utilized in cancer research.
Chemical Properties
| Molecular Formula | C16H15ClN2O |
| Molecular Weight | 286.76 |
| CAS Numbers | 2819989-68-7 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | O=C1C=2C(NC(N1)C3=C(C)C=CC=C3C)=CC=CC2Cl |
Storage and Handling
0C Short Term, -20C Long Term
References
Shifali Shishodia, et al. Selective and Cell-Active PBRM1 Bromodomain Inhibitors Discovered through NMR Fragment Screening. J Med Chem. 2022 Oct 13.