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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $51.00 | Total: $255.00 |
| 1 | 10 | $43.20 | Total: $432.00 |
| 1 | 25 | $36.60 | Total: $915.00 |
| 1 | 50 | $31.20 | Total: $1,560.00 |
| 1 | 100 | $27.00 | Total: $2,700.00 |
Overview
WDR5-0102 is a compound that inhibits the WDR5-MLL1 interface (K dis = 7 ?M, K d = 4 ?M), selectively reducing MLL1 HMT activity without affecting the human H3K4 methyltransferase SETD7 or other HMTs, including G9a, EHMT1, SUV39H2, SETD8, PRMT3, and PRMT5.
Chemical Properties
| Molecular Formula | C18H19ClN4O3 |
| Molecular Weight | 374.82 |
| CAS Numbers | 824960-50-1 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | N(C(=O)C1=C(Cl)C=CC=C1)C2=C(C=CC(N(=O)=O)=C2)N3CCN(C)CC3 |
Storage and Handling
0C Short Term, -20C Long Term
References
Lawrence HR, et al. Inhibitors of Src homology-2 domain containing protein tyrosine phosphatase-2 [Shp2] based on oxindole scaffolds. J Med Chem. 2008;51[16] 4948-4956.