Categories
- PROTAC Linker
- Protein Control Ligand
- Pathway Inhibitors
- Function Modulators
- Activators
- G Protein-Coupled Receptor Ligands
- Nuclear Receptor Ligands
- GDNF Receptors
- TNF Receptors
- Transcription Factors
- Chemokines
- Cytokine Receptors
- Biomarkers and Buffer Solutions
- Molecular Probes
- Stem Cell Research
- Alzheimer's Disease
- Apoptosis
- Cancer Research
- Epigenetics
- Metabolites
- PET/SPECT Imaging Precursors
- Customized Screening Library
- Ultra Pure Pharmacological Standard
- Tissue Microarray (TMA)
- Proteins and Antibodies
- Primary Cells
- ELISA KIT
- Natural Products
- Lab Equipments
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- Rare Chemicals
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- Antifungal
- Antioxidant
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- Molecular Glues
- SARS-CoV
Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $113.05 | Total: $565.25 |
| 1 | 10 | $95.76 | Total: $957.60 |
| 1 | 25 | $81.13 | Total: $2,028.25 |
| 1 | 50 | $69.16 | Total: $3,458.00 |
| 1 | 100 | $59.85 | Total: $5,985.00 |
Overview
MK-0533 is a novel PPAR? partial agonist for the prevention of vascular endothelial dysfunction (VED) and VED-related cardiovascular disease.
Chemical Properties
| Molecular Formula | C28H24F3NO6 |
| Molecular Weight | 527.49 |
| CAS Numbers | 668455-28-5 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | CC=1N(C=2C(C1C(=O)C3=CC=C(OC)C=C3)=CC=C(OC(F)(F)F)C2)C4=CC(O[C@@H](C(O)=O)CC)=CC=C4 |
Storage and Handling
0C Short Term, -20C Long Term
References
Acton JJ 3rd, et al. Discovery of [2R]-2-[3-{3-[[4-Methoxyphenyl]carbonyl]-2-methyl-6-[trifluoromethoxy]-1H-indol-1-yl}phenoxy]butanoic acid [MK-0533] a novel selective peroxisome proliferator-activated receptor gamma modulator for the treatment of type 2 diabetes mellitus with a reduced potential to increase plasma and extracellular fluid volume. J Med Chem. 2009 Jul 9;52[13] 3846-54.