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Quantity Discount Table - Order More To Get More Price Discount
| Quantity | mg | Unit Price ($/mg or $/Unit) | Final Price |
|---|---|---|---|
| 1 | 5 | $141.10 | Total: $705.50 |
| 1 | 10 | $119.52 | Total: $1,195.20 |
| 1 | 25 | $101.26 | Total: $2,531.50 |
| 1 | 50 | $86.32 | Total: $4,316.00 |
| 1 | 100 | $74.70 | Total: $7,470.00 |
Overview
FY-21 is a selective LSD1 inhibitor (IC50= 340 nM) that inhibits proliferation and colony formation of leukemia cells, decreases mRNA levels of the transcription factors HOXA9 and MEIS1, and can be used in the study of leukemia.
Chemical Properties
| Molecular Formula | C17H15F3N2O6 |
| Molecular Weight | 400.31 |
| Solubility | DMSO |
| Purity | 98% by HPLC |
| SMILES Code | OC1=C(O)C=C(CCNC2C3=CC=C([N+]([O-])=O)C=C3)C2=C1.OC(C(F)(F)F)=O |
Storage and Handling
0C Short Term, -20C Long Term
References
Yang C, et al. Discovery of new tetrahydroisoquinolines as potent and selective LSD1 inhibitors for the treatment of MLL-rearranged leukemia. Eur J Med Chem. 2023 Sep 5;257 115516.